Tel: 0113 4264300 | info@arterius.co.uk

Stakeholders

DIRECTORS, INVESTORS AND COLLABORATORS

1.1 DIRECTORS

Kadem Al-Lamee, CEO, Arterius Limited, was a co-founder of PolyBioMed Limited in 1996, serving as Technical Director before becoming Managing Director in 2001, when PolyBioMed was acquired by Lombard Medical Technologies. PolyBioMed was recently purchased by Bayer Materials Science. Dr Al-Lamee was integral to the development of the business throughout its history, including strategic development, fund-raising, technical development and the establishment of its intellectual property portfolio. Previously he was Principal Scientist in polymer chemistry for Innovative Technologies plc, managing research and development programmes in areas including wound dressings and coated urinary catheters. Dr Al-Lamee has extensive research and teaching experience with an MSc and PhD in Polymer Chemistry from the University of Liverpool. He has over 30 years experience in Biomaterials and Medical Devices, has published over 50 papers in international journals and holds 25 granted patents/patent applications. Dr Al-Lamee’s main interests are biomaterials, surface modifications and the coating of materials commonly used in medical devices, drug delivery systems, hydrogels for medical applications, cardiovascular devices, wound-care products, urology and tissue engineering devices. He has been successfully awarded many grants from the UK’s DTI, the Innovate UK, Yorkshire Forward, and European Commission for the research and development of healthcare projects.

Alistair Taylor, Executive Chairman, Arterius Limited has 47 years experience in the Pharmaceutical and Medical Device Industries in Europe and the US, raising over $300 million in public and private fund raisings. His previous roles include: Executive Chairman of Lombard Medical Technologies (LMT) PLC where he took LMT public in 2000, and through several subsequent fund raisings; CEO of Biocompatibles plc where Mr Taylor took this biocompatible and drug delivery coatings company through a flotation in 1995 at a valuation of $100 million – the coronary stent division was sold later to Abbott Vascular for £160 million and the contact lens division to Coopervision for £90 million; CEO of Schneider Worldwide Inc where he acquired the Swiss subsidiary Schneider AG for Pfizer Inc in 1984 for $16 million, and built the company up to over $100 million in sales through the development and commercialisation of the world’s first coronary stent, before Schneider was later sold by Pfizer Inc for $2.2 billion in 1994.

Peter Mason, Non-Executive Director, Arterius Limited, joined the Board of Directors of Arterius in 2014. Mr Mason is a Managing Director in Barclays’ Investment Banking Division. With over 16 years experience in Investment Banking, his current role, based in London, is as Head of EMEA Financial Institutions Debt Capital Markets. He holds a BSc and MEng in Engineering, Economics & Management from Oxford University, UK, and a MBA from INSEAD, France. Mr Mason is also a member of the UK’s Association of Corporate Treasurers.

Jaka Plut, Non-Executive Director, Arterius Ltd joined the Board of Directors of Arterius in 2014. He represents the main shareholder, Novoline d.o.o., on the board of Arterius, and is a business graduate with experience in marketing, sales and manufacturing with Small and Mid-sized Enterprises and start-up companies, predominantly in Slovenia.

1.2 INVESTORS

The Company funding is based on personal investments from the two founders and directors of the business, as well as from a co-investor director of Novoline d.o.o. in Ljubljana, Slovenia.
Further investments to enable the Company to undergo full human clinical trials for regulatory purposes are envisaged, and therefore approaches from angel investors, VC funds and potential strategic partners would be welcome.

1.3 RESEARCH COLLABORATORS

Neil Bressloff BA Hons (Oxon), PhD is Professor of Biomedical Engineering & Design and is Head of the Computational Engineering & Design Research Group in the Boldrewood Innovation Campus at the University of Southampton. As head of group, he is responsible for approximately 80 staff, post-doctoral researchers and PhD students. He sits on the Steering Committee for the Institute for Life Sciences, leads the Grand Challenge in Life Technologies and leads the Bioengineering and Human Factors Faculty Theme. He has over 20 years’ experience in computational engineering and design with allied expertise in computational fluid dynamics, finite element analysis and high performance computing, particularly applied in the field of cardiovascular engineering. He has published over 75 learned articles and won over £1.5m in grants in recent years, largely engaged with industry.

Professor Phil Coates, FR Eng (Professor of Polymer Engineering, Bradford University) is Director of the Polymer Centre of Industrial Collaboration, the Advanced Materials Engineering RKT Centre, and the International Centre for Polymer Microprocessing (a joint laboratory with Sichuan University). The research targets high value polymer products for a range of sectors – healthcare technology (including bioresorbable polymers for orthopaedic applications), pharmaceuticals processing, optical, automotive and advanced materials developments, including nanocomposites and reactive grafting, all with pioneering in-process measurement and modelling. He has published extensively – over 300 papers, in scientific journals and has co-authored 9 books, and edited 7 books. He holds 12 patents. He is Chief Editor of the IoM3 international journal, Plastics, Rubber and Composites: Macromolecular Engineering

Dr Adrian Kelly, BEng (Hons) PhD CEng (Reader in Polymer Engineering at the University of Bradford). His research interests include pharmaceutical polymer engineering, process monitoring, thermal optimisation, nanocomposites, biopolymers and recyclates. In 2010 he co-founded the Centre for Pharmaceutical Engineering Science with colleagues in Engineering and Life Sciences; he is also active in the Centre of Advanced Materials Engineering and the Centre for Polymer Micro and Nano Technology.

Professor Morgan Alexander (Professor of Biomedical Surfaces, Nottingham University) is the Director of the EPSRC Programme Grant in Next Generation Biomaterials Discovery, a Royal Society-Wolfson Research Merit Award holder and a Wellcome Trust Senior Investigator. His work involves developing materials for application in human healthcare and characterising relationships between surface structure and biological properties. Understanding these relationships is critical to the development of next generation biomaterials and it is the theme running through his group’s work across a variety of areas spanning controlling bacterial adhesion to stem cell response for application in medical devices and cell manufacture.
Dr Nicolas Foin is Scientific Lead for Medtech research at the National Heart Research Institute Singapore and Adjunct Associate Professor at Duke-National University of Singapore Graduate Medical School. His research expertise focuses on treatment of coronary heart diseases using minimally invasive approach, as well as pre-clinical diseases models and intravascular imaging. Regular speaker in international cardiac interventional congresses, he has to date published over 60 publications and book chapters in the field of cardiovascular interventions and intravascular OCT imaging. He has also collaborated with several large medical device companies and start-ups on new product developments.

1.4 CLINICAL COLLABORATORS

Dr Justin Davies is a leading clinical academic in the field of interventional cardiology. Based as a consultant interventional cardiologist at Hammersmith Hospital, part of Imperial College Healthcare NHS Trust London, he has pioneered the development of several new clinical techniques including iFR (instant wave-free ratio) and iFR SCOUT both of which make use of a better understanding of coronary haemodynamics allowing the evaluation of the severity of a coronary stenosis without the need for administration of powerful vasodilator drugs. Although currently a practicing interventional consultant cardiologists Justin’s science training was a doctorate in fluid dynamics and computational programming.
The holder of 15 patents, he has published widely in the field of hypertension, coronary and large artery physiology and is the winner of many national and international awards. He has several international collaborations, and is the co-principal investigator of the ADVISE studies, the DEFINE-FLAIR, and ORBITA studies.

Dr Rasha Al-Lamee is an Interventional Cardiologist at Imperial College Healthcare NHS Trust. She studied at the University of Oxford and University College London. She went onto complete her training as a junior doctor on the Barts and the London Medical rotation before being appointed as a Specialist Registrar on the North West London Cardiology rotation in 2006. She has 9 years of Cardiology experience and completed three years of Interventional Fellowship training at Hammersmith Hospital in London. She also spent one year training as an Interventional Fellow under the supervision of Professor Antonio Colombo in Milan. She completed specialist training in 2013 and is currently working as an Interventional Cardiologist at Imperial College NHS Healthcare Trust and a Clinical Researcher at Imperial College London.

Her sub-speciality interests are complex coronary intervention, coronary physiology and invasive intravascular assessment. She is currently leading the ORBITA trial as part of a PhD programme under the supervision of Dr Justin Davies and Professor Darrel Francis. At Imperial College she is actively involved in the development and recruitment of a number of multi-centre clinical trials. She had over 20 peer-reviewed publications and has presented at international Cardiology conferences worldwide throughout her clinical career.